drive systems and fluid power technology

EMO Hannover 2017 Machine Tools Roundtable

A computational model of the hearts mitral valve presurgery. The new imaging technology is so accurate, it can be used in a clinical setting to provide patient-specific models, so surgeons can tailor treatments for mitral valve diseases on a case by case basis.

Credit: Cockrell School of Engineering, The University of Texas at Austin

Heart valve modeling technique; customized medical care

Engineers develop noninvasive way to simulate repairs to the hearts mitral valve allowing surgeons to provide patient-specific treatments.

Edited by Elizabeth Engler ModicDesign/EngineeringDevices/Implants/Equipment

Engineers atThe University of Texas at Austinhave developed a new non-invasive technique for simulating repairs to the hearts mitral valve with levels of accuracy reliable enough for use in a clinical setting.Mitral valve (MV) diseaseis one of the most common valve-related heart conditions, newly diagnosed in 5 million Americans each year. Left unchecked, MV disease can lead to heart failure and/or stroke. This advance in computational modeling technology allows surgeons to provide patient-specific treatments, a development that will improve the long-term efficacy of current medical approaches.

Led by Michael Sacks, a professor in the Department of Biomedical Engineering in the Cockrell School of Engineering, the team outlined their computational modeling technique for imaging MV leaflets flaps located on the base of the valve that open and close to regulate blood flow from the left atrium to left ventricle of the heart in recent issues of theInternational Journal for Numerical Methods in Biomedical Engineeringand theAnnals of Biomedical Engineering.

The MV plays a crucial role in maintaining healthy blood flow in the heart, but normal function can be compromised in a number of ways. For instance, heart attacks may disrupt the MV leaflets capacity to close properly, resulting in blood leaking back into the hearts left atrium. The importance of healthy MV function is thus widely understood within the medical community, but there is not a consensus on how best to treat common MV disorders such as regurgitation, prolapse and mitral valve stenosis.

Until now, there has been a lack of accurate modeling approaches available to surgeons for predicting the best surgical methods to restore MV function.

Heart valves are very difficult to study. They are complex structures that move incredibly fast and are located inside the heart, making them extremely difficult to image, says Sacks, who also serves as director of the James T. Willerson Center for Cardiovascular Modeling and Simulation in the universitys Institute for Computational Engineering and Sciences. Our new computational model provides surgeons with a tool for the prediction of postsurgical outcomes from clinically obtained presurgical data alone.

Sacks has spent most of his academic career analyzing and modeling heart valve function. Recent advances in computational and 3D imaging technologies have made it possible for Sacks and his team to noninvasively and accurately acquire the in vivo (or living) geometry of the MV leaflets in patients from real-time 3D echocardiography a clinical technique that uses sound waves to monitor heart function.

The UT teams computational model was developed in collaboration with researchers from Penn Medicine and Georgia Tech.

Our models combined the complete 3D geometry of the mitral valve in the open and closed states, making possible an unparalleled level of predictive accuracy, Sacks says. To model the MV leaflets, we then integrated into the MV models the structure and mechanical properties of the internal constituents, such as the collagen fibers which make up most of the valve, to develop attribute-rich complete MV models.

Several studies have shown significant deficiencies in the long-term success of current surgical approaches to treating common heart valve diseases. Up to 60 percent of patients who have undergone MV regurgitation surgery report recurrence just two years after the surgery.

Cardiac surgeons must decide upon the best possible treatment for heart valve repair without knowing all the facts, notes Dr. Robert Gorman, professor of surgery in the Perelman School of Medicine at the University of Pennsylvania and a key collaborator on the study. Most rely on their own experiences or how they were taught to perform valve repair surgery in medical school.

With the researchers new predictive technique, surgeons wont have to take the previous one-size-fits-all approach to MV leaflet repair.

The computational modeling tool weve developed will eliminate a lot of the uncertainty and allow for patient specificity, Gorman says. This will be transformative for those working in the field.

The next step for Sacks and his research team is to commercialize their technique.

Once heart surgeons gain access to this tool in a clinical setting, we anticipate significant improvements in the long-term well-being of patients whove undergone mitral valve surgery, he says.

The study was funded by the National Institutes of Health.

There are approximately 560 GROB employees located on-site, with space to allow for future growth.

Edited by Elizabeth Engler ModicMachining/Metal CuttingPeople/Facilities

Bluffton, Ohio Grobs new 45,918ft2, three-story facility will feature an open floor plan and flexible workspace designed to help foster greater collaboration, innovation, and creativity. Throughout the campus, a variety of working and gathering spaces will be available to employees to provide maximum flexibility for every working situation.

We had the opportunity to build something new, giving every consideration to what kind of space our employees would be excited to work in, as well as represent the design and technology of our products saysGrob System Inc. CEO, Michael Hutecker.

It was important for us to continue our commitment to the Village of Bluffton and the state of Ohio. Weve been a huge part of this community for almost 30 years, and were pleased to bring what we believe is one of the states top work environments to the area.

There are approximately 560 Grob employees located on-site, with space to allow for future growth. The campus boasts a full-service kitchen that offers a free lunch, as well as an outside patio dining area.

This building makes a bold statement about our product, while still paying tribute to our roots and demonstrating our journey for the future.

We feel the addition to our campus will aid in drawing in the communities top talent. Resumes can always be sent to.

GROB Systems, Inc. started their operations in Bluffton, Ohio in 1991 as a manufacturer of machine tool equipment, primarily for the automotive industry. They are a subsidiary of Grob-Werke GmbH & Co. KG, located in Mindelheim, Germany. The Grob Group currently consists of manufacturing facilities in Germany, Brazil, United States and China. In addition to these sites, they also have sales and service facilities globally.

Grob Systems apprenticeship program began in 1991. Grob is proud to have such a valuable program in place. Not only are they training their workforce for the future, but they are continuing to strengthen the manufacturing presence in Ohio.

Grob Systems core competency is in manufacturing systems:

Medical device manufacturer expects 2019 organic net sales growth to be in the range of 6.5% to 7.5%.

Edited by Elizabeth Engler ModicDevices/Implants/Equipment

Kalamazoo, Michigan Strykerreported operating results for thefourth quarter and full year of 2018and offered a 2019 outlook.

Reported net sales increased 9.4% to $3.8 billion

Reported operating income margin of 18.4%

Adjusted operating income margin(1) expanded 50 bps (30 bps excluding ASC 606(2)) to 27.5%

Reported EPS increased 924.2% to $5.44

Adjusted EPS(3) increased 11.2% to $2.18, at the high end of guidance range

Reported net sales increased 9.3% to $13.6 billion

Reported operating income margin of 18.7%

Adjusted operating income margin(1) expanded 70 bps (40 bps excluding ASC 606(2)) to 25.9%

Reported EPS increased 248.5% to $9.34

Adjusted EPS(3) increased 12.6% to $7.31, exceeding the high end of guidance range

We had an excellent finish to 2018 with the best organic sales growth in a decade, and strong adjusted earnings performance, said Kevin A. Lobo, Chairman and Chief Executive Officer. Our multi-year momentum reflects the strength of our diversified model, progress on globalization and outstanding people and culture. We are well positioned to deliver for our customers, employees and shareholders in 2019 and beyond.

Sales analysis (percentages exclude ASC 606(2) adoption impact)

Consolidated net salesof $3.8 billion and $13.6 billion increased 10.1% and 10.2% in the quarter and full year and 11.3% and 9.8% in constant currency. Organic net sales increased 8.6% and 7.9% in the quarter and full year including 10.1% and 9.3% from increased unit volume partially offset by 1.5% and 1.4% from lower prices.

Orthopaedics net salesof $1.4 billion and $5.0 billion increased 5.9% and 6.4% in the quarter and full year and 7.0% and 5.9% in constant currency. Organic net sales increased 7.0% and 5.9% in the quarter and full year including 8.9% and 8.1% from increased unit volume partially offset by 1.9% and 2.2% from lower prices.

MedSurg net salesof $1.7 billion and $6.0 billion increased 9.9% and 10.1% in the quarter and full year and 11.1% and 10.0% in constant currency. Organic net sales increased 10.1% and 8.6% in the quarter and full year including 11.3% and 9.3% from increased unit volume partially offset by 1.2% and 0.7% from lower prices.

Neurotechnology and Spine net salesof $0.7 billion and $2.6 billion increased 20.1% and 18.6% in the quarter and full year and 21.4% and 18.0% in constant currency. Organic net sales increased 8.4% and 10.6% in the quarter and full year including 10.2% and 12.2% from increased unit volume partially offset by 1.8% and 1.6% from lower prices.

We expect 2019 organic net sales growth to be in the range of 6.5% to 7.5% and expect adjusted net earnings per diluted share(5) to be in the range of $8.00 to $8.20. We expect adjusted net earnings per diluted share(5) to be in the range of $1.80 to $1.85 in the first quarter.

Companies to discuss growth of artificial intelligence (AI) and machine learning.

By Michelle JacobsonAutomation/Robotics

Hannover, Germany Manufacturing technology companies will showcase the latest in the digital networking of people and machines in the age of artificial intelligence atHANNOVER MESSE 2019, April 1-5, 2019 in Hannover, Germany.

With an anticipated 6,500 companies from 75 nations in attendance, the show will be spotlighting components and system solutions for tomorrows industrial production and energy systems. Exhibitors will include industry leaders of automation, robotics, industrial software, drive systems and fluid power technology, energy technologies, subcontracting, and research and development.

Innovative digital technologies have continued to push the industry forward, allowing manufacturing processes to become increasingly more accurate, flexible, and cost-efficient. Encompassing the lead theme of Industrial Intelligence, the show will highlight the importance of artificial intelligence and how humans play a key role in enabling this technology through expanded knowledge and training. To demonstrate this collaborative relationship, there will be more than 100 user examples of machine learning, including the first-ever 5G test field that will be located in Hall 16. Here, attendees will be provided with a glimpse of the future with a demonstration of the fifth generation of mobile communications.

HANNOVER MESSE 2019 will also debut theFuture of Work in Industryconference, where thought leaders will share experiences and insights about the impact of digitization. On April 3, visitors can learn about industry 4.0 and the associated effects on the working world of the future, as well as innovated solutions. Speakers will include philosopher and author Richard David Precht, Siemens Chief Human Resources Officer Janina Kugel and human cyborg Ralf Neuhäuser.

A returning theme of the show will be lightweight design, which is important for electric mobility. TheLightweight Design Summitwill open a dialogue between politics, business, and research on topics relevant to lightweight construction. Panel discussions that focus on material and resource efficiency, innovative engineering, and digitized development chains, will take place on April 2.

The first Industrial Pioneers Summit,hosted on April 2, will look into the future to determine what may come after Industry 4.0. Thought leaders and innovators will share insights and predictions for future developments and scenarios, shaping a vision for 2025.

This years chosen partner is Sweden, a country that shares in the innovation and digital transformation that the show represents. Sweden will promote the countrys networking, trade, and investment with its global partners.

Hill-Rom Centrella Smart+ Bed with EarlySense

Photo courtesy of Hill-Rom & EarlySense

EarlySenses integrated continuous monitoring of millionth patient

The company expects to monitor three million patients in coming three years helping the industry save more than $1 billion.

Edited by Elizabeth Engler ModicDesign/EngineeringDevices/Implants/Equipment

Ramat Gan, Israel EarlySense officials announced that its 10,000 installed systems have surpassed one million patients monitored. With growth stemming from within the company itself, and via partners such as Philips andHill-Rom, EarlySenseexpects to monitor an additional estimated three million patients in the next three years.

EarlySenses continuous monitoring sensors are projected to help global medical institutions collectively save more than $3 billion over the next five years, with per bed savings of more than $10,000 per year. These savings are realized due toEarlySenseassisting health clinicians:

Over the past year, EarlySense helped clinicians save more than 180,000 patient hospital days, assisted in the prevention of more than 14,000 pressure ulcers, and also helped hospitals save more than three thousand lives.

Every day, one thousand patients die unnecessarily in hospitals across the United States. Tools like our advanced sensing and data analytics solutions increase the number of patients continuously monitored, assisting clinicians to drastically reduce that difficult statistic, says Avner Halperin, co-founder and CEO of EarlySense. Surpassing one million patients is a tremendous milestone for EarlySense and for healthcare systems worldwide, proving that continuous monitoring is becoming the new standard of care in the healthcare industry. As a result of our partnership with Hill-Rom, we expect this number to grow exponentially, empowering clinicians to save thousands of lives and significantly reducing costs for healthcare systems across the globe.

Placed under a bed mattress, EarlySenses patented sensor uses artificial intelligence and big data analysis to accurately monitor heart rate, respiratory rate, motion, and sleep.

[1] Brown, Harvey et al. Continuous Monitoring in an Inpatient Medical-Surgical Unit: A Controlled Clinical Trial. The American Journal of Medicine, Volume 127, Issue 3, 226 232

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